Mouse Models
SPG7
Publication
eSpg7 KO
Identification
- Causal gene(s)
- SPG7
- Repeat size or mutation
- Spg7 and Afg3l1 full body knockout
- Animal model
- Mouse
Model Details
- Mouse strain / background
- C57BL/6N
- Type of model
- knockout
Phenotype
- Progression
- progressive
- Hallmark features
- Progressive spastic-ataxia, degeneration of axons in spinal cord and cerebellum, mitochondrial abnormalities
Source & Publications
- Originating lab / institution
- University of Cologne
- Links to publications or public resources
Some fields are restricted to approved researchers. Log in to view them.