Mouse Models EA1 Publication

Kcna-/- mice

Identification

Causal gene(s)
KCNA1
Repeat size or mutation
Homozygous Kcna1 knockout
Animal model
Mouse

Model Details

Mouse strain / background
Different background strains
Type of model
knockout

Phenotype

Hallmark features
Episodic eye blinking, twitching of vibrissiae, forelimb paddling, arrested motion, hyperstartle response, spontaneous seizures, motor seizures, increased mortality

Source & Publications

Originating lab / institution
University of Washington

Twenty Twenty-Five

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