Mouse Models
AVED
Publication
alpha-TTP(-/-) mice
Identification
- Causal gene(s)
- TTPA
- Repeat size or mutation
- Homozygous Ttpa knock-out mice
- Animal model
- Mouse
Model Details
- Mouse strain / background
- C57BL/6J
- Type of model
- knockout
Transgenic Construct
- Transgenic construct: details
- Targeting vector where the entire exon 1 was replaced by a neomycin-resistance cassette
Phenotype
- Hallmark features
- Lower plasma α-tocopherol levels, infertility in female mice
Source & Publications
- Originating lab / institution
- Chugai Pharmaceutical Co., Ltd.
- Links to publications or public resources
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