Mouse Models
SCAR8/ARCA1
Publication
Nes1g FLAG/FLAG
Identification
- Causal gene(s)
- SYNE1
- Repeat size or mutation
- KASH reporter' mouse model
- Animal model
- Mouse
Model Details
- Mouse strain / background
- C57/BL6
- Type of model
- CRISPR/Cas9-induced FLAG C-terminal tag
Transgenic Construct
- Transgenic construct: details
- 3XFLAG tag followed by a STOP codon (3XFLAG/STOP) was inserted within exon-1 both upstream and in frame with the coding sequence of the KASH domain of Syne1. Here, the KASH domain is replaced by 3xFLAG in Syne1 transcripts containing exon-2
Source & Publications
- Originating lab / institution
- Washington University School of Medicine
- Links to publications or public resources
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