Mouse Models MSA/OPCA Publication

PDGF-ß-EGFP-α-Syn transgenic mouse

Identification

Causal gene(s)
Sporadic
Repeat size or mutation
expressing a stable enhanced green fluorescent protein (eGFP) tagged in the C-terminal site of a human (h)α-synuclein construct
Animal model
Mouse

Model Details

Mouse strain / background
C57BL/6xDBA/2 F1
Type of model
transgenic

Transgenic Construct

Transgenic construct: sequence type
cDNA for human α-synuclein expression
Transgenic construct: details
eGFP was fused to the C-terminal site of hα-synuclein
Promoter: gene
PDGF-ß
Promoter: species
Human

Source & Publications

Originating lab / institution
University of California

Twenty Twenty-Five

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