Mouse Models
SPG7
Publication
Spg7-/- mice
Identification
- Causal gene(s)
- SPG7
- Repeat size or mutation
- Spg7 homozygous knockout
- Animal model
- Mouse
Model Details
- Mouse strain / background
- C57BL/6-129Sv
- Type of model
- knockout
Phenotype
- Progression
- progressive
- Hallmark features
- Loss of body weight, scoliosis, abnormal gait, motor impairment, distal axonopathy, mitochondrial abnormalities, delay of retrograde transport
Source & Publications
- Originating lab / institution
- Telethon Institute of Genetics and Medicine
- Links to publications or public resources
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