Mouse Models
SCA37
Publication
Yotari mice
Identification
- Research Resource Identifier (RRID)
- rridtest
- Causal gene(s)
- DAB1
- Repeat size or mutation
- Spontaneous autosomal recessive mutation in Dab1
- Animal model
- Mouse
Model Details
- Mouse strain / background
- 129/SvJ and C57BL/6J Jcl
Transgenic Construct
- Transgenic construct: details
- a spontaneous replacement of genomic nucleotides with a long interspersed nuclear element (L1) fragment in the Dab1 gene.
Phenotype
- Hallmark features
- Unstable gait, tremor, premature death, hypoplastic cerebellum without foliation, distorted laminar structure of cerebral cortex and hippocampal formation
Source & Publications
- Originating lab / institution
- University of Tokyo
Contact
- Contact name
- Ralf Santbergen
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